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Neuroscience Neurotransmitter Transporters Glutamate

RuBi-Glutamate, caged-glutamate compound (ab120408)

Price and availability

140 716 ₸

Availability

Order now and get it on Friday February 26, 2021

Key features and details

  • Novel caged-glutamate compound, uncaged by visible light
  • CAS Number: 2417096-44-5
  • Soluble in water to 20 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    RuBi-Glutamate, caged-glutamate compound
  • Description

    Novel caged-glutamate compound, uncaged by visible light
  • Biological description

    Novel caged-glutamate compound based on ruthenium photochemistry. Excited with visible wavelengths and releases glutamate after one- or two-photon excitation. It has high quantum efficiency and can be used at low concentrations. Enables the photoactivation of neuronal dendrites and circuits with visible or two-photon light sources, achieving single cell, or even single spine, precision.

    Also available in simple stock solutions (ab146718) - add 1 ml of water to get an exact, ready-to-use concentration.

  • General notes

    RuBi-Glutamate is light sensitive and it is recommended that the compound is protected from light.

    Sold under license from Columbia University; Patent Pending.

  • CAS Number

    2417096-44-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (Bis(2,2'-bipyridine-N,N')trimethylphosphine)-(S)-1-aminopropane-1,3-dicarboxylic acid ruthenium(2+) complex sodium hexafluorophosphate salt
  • Molecular weight

    948.56
  • Molecular formula

    C28H33N5O4PRu.Na(PF6)2
  • PubChem identifier

    90488860
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in water to 20 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CP(C)C.C1=CC=NC(=C1)C2=CC=CC=N2.C1=CC=NC(=C1)C2=CC=CC=N2.C(CC(=O)[O-])C(C(=O)[O-])N.F[P-](F)(F)(F)(F)F.F[P-](F)(F)(F)(F)F.[Na+].[Na+].[Ru+2]
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Amino Acids
    • Glutamate
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Glutamate Receptors
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR
    • Biochemicals
    • Product Range
    • Just Add Water
    • Biochemicals
    • Chemical Type
    • Amino Acid
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Chemical Type
    • Caged Compounds
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Glutamate
    • Broad spectrum / non-selective
    • Agonists
    • Biochemicals
    • Research Area
    • Addiction
    • Glutamate
    • Broad spectrum / non-selective
    • Agonists
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Glutamate
    • Broad spectrum / non-selective
    • Agonists
    • Biochemicals
    • Research Area
    • Depression
    • Glutamate
    • Broad spectrum / non-selective
    • Agonists
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Glutamate
    • Broad spectrum / non-selective
    • Agonists
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Glutamate
    • Broad spectrum / non-selective
    • Agonists
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Glutamate
    • Broad spectrum / non-selective
    • Agonists
    • Biochemicals
    • Research Area
    • Stroke
    • Glutamate
    • Broad spectrum / non-selective
    • Agonists
    • Kits/ Lysates/ Other
    • Tools and Reagents
    • Fluorescent dyes and reagents

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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