Rocaglamide, inhibitor of NF-kappaB activation (ab142130)
Key features and details
- Potent inhibitor of NF-κB activation
- CAS Number: 84573-16-0
- Purity: > 98%
- Soluble in DMSO and ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Rocaglamide, inhibitor of NF-kappaB activation -
Description
Potent inhibitor of NF-κB activation -
Biological description
Potent inhibitor of NF-κB activation. Suppresses cytokine production (IFN-γ, TNF-α, IL-2 and IL-4) and inhibits NF-AT in T cells. -
Purity
> 98% -
CAS Number
84573-16-0 -
Chemical structure
Properties
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Chemical name
(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide -
Molecular weight
505.56 -
Molecular formula
C29H31NO7 -
PubChem identifier
331783 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO and ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C)C(=O)C1C(C2(C(C1O)(C3=C(C=C(C=C3O2)OC)OC)O)C4=CC=C(C=C4)OC)C5=CC= CC=C5 -
Source
Synthetic
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Research areas
