Ro 25-6981 maleate salt, NR2B antagonist (ab120290)
Key features and details
- NR2B antagonist
- CAS Number: 169274-78-6
- Purity: > 98%
Soluble in water to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ro 25-6981 maleate salt, NR2B antagonist -
Description
NR2B antagonist -
Alternative names
- Ro25-6981 maleate salt
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Purity
> 98% -
CAS Number
169274-78-6 -
Chemical structure
Properties
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Chemical name
[R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate -
Molecular weight
455.55 -
Molecular formula
C22H29NO2.C4H4O4 -
PubChem identifier
53250677 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
SMILES
O=C(O)/C=CC(=O)O.Oc1ccc(cc1)[C@H](O)[C@@H](C)CN2CCC(CC2)Cc3ccccc3Source
Synthetic
Research areas
Images
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Functional Studies - Ro 25-6981 maleate salt, NR2B antagonist (ab120290) Image from Wills TA et al., Proc Natl Acad Sci U S A. 2012;109(5):E278-87. Fig 6(B).; doi: 10.1073/pnas.1113820109.Averaged time courses of NMDA receptor-isolated synaptic field potentials in dorsal lateral bed nucleus of the stria terminalis following 60 minutes of Ro 25-6981 (0.2, 2.0, or 10 μM; ab120290) in slices from naive adult male C57BL/6J mice.