RN-1 dihydrochloride (ab254240)
Key features and details
- Potent, cell-permeable LSD-1 inhibitor.
- CAS Number: 1781835-13-9
- Purity: > 97%
DMSO: 8 mg/mL
Water: 8 mg/mL
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
RN-1 dihydrochloride -
Description
Potent, cell-permeable LSD-1 inhibitor. -
Biological description
Potent, cell-permeable LSD-1 inhibitor (IC50 = 70 nM). Selective for LSD-1 versus MAO-A (IC50 = 0.51 μM) and MAO-B (IC50 = 2.79 μM). Impairs long-term, but not short-term memory in mice. Brain penetrant following systemic administration.
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Purity
> 97% -
General notes
Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. Protect from air and moisture.
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CAS Number
1781835-13-9 -
Chemical structure
Properties
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Chemical name
1-(4-Methylpiperazin-1-yl)-2-[[(1R,2S)-2-(4-phenylmethoxyphenyl)cyclopropyl]amino]ethenone dihydrochloride
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Molecular weight
452.42 -
Molecular formula
C23H29N3O2.2HCl -
PubChem identifier
90488995 -
Storage instructions
Shipped at 4°C. Store at -20°C. Store under desiccating conditions. -
Solubility overview
DMSO: 8 mg/mL
Water: 8 mg/mL
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Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN1CCN(CC1)C(=O)CN[C@@H]2C[C@H]2C3=CC=C(C=C3)OCC4=CC=CC=C4.Cl.Cl -
Source
Synthetic
