Reveromycin A, G1 phase cell cycle inhibitor (ab142697)
Key features and details
- G1 phase cell cycle inhibitor and selective protein synthesis inhibitor
- CAS Number: 134615-37-5
- Purity: > 98%
- Soluble in ethanol, methanol or DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Reveromycin A, G1 phase cell cycle inhibitor -
Description
G1 phase cell cycle inhibitor and selective protein synthesis inhibitor -
Biological description
G1 phase cell cycle inhibitor and selective protein synthesis inhibitor. Induces apoptosis in vitro. Inhibits eukaryotic cell growth. Antitumor, antifungal and bone resorption agent. Active in vitro and in vivo. -
Purity
> 98% -
CAS Number
134615-37-5 -
Chemical structure
Properties
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Chemical name
(2E,5S,6E,8E)-10-[(2S,3R,6S,8R,9S)-3-Butyl-2-[(1E,3E)-4-carboxy-3-methylbuta-1,3-dienyl]-3-(3-carboxypropanoyloxy)-9-methyl-1,7-dioxaspiro[5.5]undecan-8-yl]-5-hydroxy-4,8-dimethyldeca-2,6,8-trienoic acid -
Molecular weight
660.79 -
Molecular formula
C36H52O11 -
PubChem identifier
56840987 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol, methanol or DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCC1(CCC2(CCC(C(O2)CC=C(C)C=CC(C(C)C=CC(=O)O)O)C)OC1C=CC(=CC(=O)O)C)OC(=O)CCC(=O)O -
Source
Synthetic
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Research areas
