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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Recombinant mouse TSLP protein (ab181941)

Key features and details

  • Expression system: Insect cells
  • Purity: > 99% SDS-PAGE
  • Active: Yes
  • Tags: His tag N-Terminus
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant mouse TSLP protein
    See all TSLP proteins and peptides
  • Biological activity

    The ED50 tested in a Nag8/7 cell proliferation assay was 0.15 ng/ml, corresponding to a specific activity of approximately 6x106 Units/mg.

  • Purity

    > 99 % SDS-PAGE.

  • Expression system

    Insect cells
  • Accession

    Q9JIE6
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      YNFSNCNFTSITKIYCNIIFHDLTGDLKGAKFEQIEDCESKPACLLKIEY YTLNPIPGCP SLPDKTFARRTREALNDHCPGYPETERNDGTQEMAQEV QNICLNQTSQILRLWYSFMQSP E
    • Predicted molecular weight

      14 kDa
    • Amino acids

      20 to 140
    • Tags

      His tag N-Terminus
    • Additional sequence information

      Mature protein.

Preparation and Storage

  • Alternative names

    • Thymic stromal lymphopoietin
    • Thymic stromal lymphopoietin protein TSLP
    • Tslp
    • TSLP protein
    • TSLP_HUMAN
    see all
  • Function

    Cytokine that induces the release of T cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.
  • Tissue specificity

    Expressed in a number of tissues including heart, liver and prostate.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession Q969D9 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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