Recombinant Mouse SLAMF7/CS1 protein (His tag) (ab276793)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Mouse SLAMF7/CS1 protein (His tag)
See all SLAMF7/CS1 proteins and peptides -
Purity
> 95 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Protein fragmentAnimal free
NoNature
Recombinant-
Species
Mouse -
Sequence
MARFSTYIIF TSVLCQLTVT AASGTLKKVA GALDGSVTFT LNITEIKVDY VVWTFNTFFL AMVKKDGVTS QSSNKERIVF PDGLYSMKLS QLKKNDSGAY RAEIYSTSSQ ASLIQEYVLH VYKHLSRPKV TIDRQSNKNG TCVINLTCST DQDGENVTYS WKAVGQGDNQ FHDGATLSIA WRSGEKDQAL TCMARNPVSN SFSTPVFPQK LCEDAATDLT SLRG -
Predicted molecular weight
24 kDa including tags -
Molecular weight information
The recombinant mouse SLAMF7 consists of 213 amino acids with the predicted molecular mass of 23.7 kDa. As a result of glycosylation, the apparent molecular mass of rm SLAMF7 is approximately 35-50 kDa in SDS-PAGE under reducing conditions. -
Amino acids
1 to 224 -
Tags
His tag C-Terminus -
Additional sequence information
Predicted N-terminus: Ser 23.
Specifications
Our Abpromise guarantee covers the use of ab276793 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- 19A
- 19A24 protein
- CD 319
see all -
Relevance
SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms. -
Cellular localization
Membrane; Single-pass type I membrane protein.
Images
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SDS-PAGE - Recombinant Mouse SLAMF7/CS1 protein (ab276793)SDS-PAGE analysis of ab276793
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276793 has not yet been referenced specifically in any publications.
Preparation and Storage
- 19A
- 19A24 protein
- CD 319
Images
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SDS-PAGE - Recombinant Mouse SLAMF7/CS1 protein (ab276793)SDS-PAGE analysis of ab276793
