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Immunology Innate Immunity Macrophage / Inflamm.

Recombinant Mouse M-CSF protein (ab169716)

Price and availability

180 921 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Expression system: Yeast
  • Purity: > 95% SDS-PAGE
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Mouse M-CSF protein
    See all M-CSF proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    ab169716 was purified by Ion-exchange chromatography.
  • Expression system

    Yeast
  • Accession

    P07141
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      AKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKPDCNC LYPKATPSSD PASASPHQPP APSMAPLAGL AWDDSQRTEG SSLLPSELPL RIEDPGSAKQ RPPRSTCQTL E
    • Predicted molecular weight

      26 kDa
    • Amino acids

      32 to 262

Preparation and Storage

  • Alternative names

    • Colony stimulating factor 1
    • Colony stimulating factor 1 (macrophage)
    • Colony stimulating factor macrophage specific
    • CSF 1
    • CSF-1
    • CSF1
    • CSF1_HUMAN
    • Csfm
    • Lanimostim
    • M CSF
    • M-CSF
    • Macrophage colony stimulating factor
    • Macrophage Colony Stimulating Factor 1
    • MCSF
    • MGC31930
    • Processed macrophage colony-stimulating factor 1
    see all
  • Function

    Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.
  • Post-translational
    modifications

    Glycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate.
    Isoform 1 is N- and O-glycosylated. Isoform 3 is N-glycosylated.
  • Cellular localization

    Cell membrane and Secreted > extracellular space.
  • Target information above from: UniProt accession P09603 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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