Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Mouse LIGHT/TNFSF14 protein (ab50095)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Mouse LIGHT/TNFSF14 protein
    See all LIGHT/TNFSF14 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Greater than 98% by SDS-PAGE and HPLC analyses.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV

    • Specifications

    Our Abpromise guarantee covers the use of ab50095 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized

    • Additional notes

       This product was previously labelled as LIGHT

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    • Reconstitution
      Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.

    General Info

    • Alternative names

      • CD 258
      • CD258
      • CD258 antigen
      • Delta transmembrane LIGHT
      • Herpes virus entry mediator ligand
      • Herpesvirus entry mediator A
      • Herpesvirus entry mediator ligand
      • herpesvirus entry mediator-ligand
      • HVEM L
      • HVEM-L
      • HVEML
      • Ligand for herpesvirus entry mediator
      • LIGHT
      • LTg
      • soluble form
      • TNF14
      • TNF14_HUMAN
      • TNFSF 14
      • Tnfsf14
      • TNFSF14 protein
      • TR 2
      • TR2
      • Tumor necrosis factor (ligand) superfamily, member 14
      • Tumor necrosis factor ligand superfamily member 14
      • Tumor necrosis factor ligand superfamily, member 14
      • Tumor necrosis factor receptor like 2
      • tumor necrosis factor receptor-like 2
      • Tumor necrosis factor superfamily member 14
      • Tumor necrosis factor superfamily member LIGHT
      see all

    • Function

      Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.

    • Tissue specificity

      Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.

    • Sequence similarities

      Belongs to the tumor necrosis factor family.

    • Post-translational
      modifications

      N-glycosylated.
      The soluble form of isoform 1 derives from the membrane form by proteolytic processing.

    • Cellular localization

      Cytoplasm; Secreted and Cell membrane.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab50095? Please let us know so that we can cite the reference in this datasheet.

ab50095 has not yet been referenced specifically in any publications.

Preparation and Storage

  • CD 258
  • CD258
  • CD258 antigen

Images

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