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Cancer Tumor immunology Cytokines Interferons

Recombinant mouse Interferon alpha 1 protein (Active) (ab259386)

Recombinant mouse Interferon alpha 1 protein (Active) (ab259386)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Cell Culture, SDS-PAGE, HPLC, MS, Functional Studies

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Preparation and Storage

  • Alternative names

    • IFL
    • IFN
    • IFN alpha
    • IFN alpha 1/13
    • IFN alpha 1b
    • IFN alphaD
    • IFN-alpha-1/13
    • IFNA@
    • IFNA1
    • IFNA1_HUMAN
    • IFNA13
    • Interferon alpha 1
    • Interferon alpha-1/13
    • Interferon alpha-D
    • Interferon alpha1
    • Interferon, alpha 13
    • LeIF D
    see all
  • Function

    Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
  • Sequence similarities

    Belongs to the alpha/beta interferon family.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P01562 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • Functional Studies - Recombinant mouse Interferon alpha 1 protein (Active) (ab259386)
    Functional Studies - Recombinant mouse Interferon alpha 1 protein (Active) (ab259386)

    Cytopathic Effect Inhibition Assay of L929 cells against Encephalomyocarditis virus.

    ED50  7 x 10-3 ng/mL, corresponding to a specific activity of 1.43 x 108 units/mg.

  • SDS-PAGE - Recombinant mouse Interferon alpha 1 protein (Active) (ab259386)
    SDS-PAGE - Recombinant mouse Interferon alpha 1 protein (Active) (ab259386)

    SDS-PAGE analysis of ab259386.

  • HPLC - Recombinant mouse Interferon alpha 1 protein (Active) (ab259386)
    HPLC - Recombinant mouse Interferon alpha 1 protein (Active) (ab259386)

    Purity by HPLC ≥95%

  • Mass Spectrometry - Recombinant mouse Interferon alpha 1 protein (Active) (ab259386)
    Mass Spectrometry - Recombinant mouse Interferon alpha 1 protein (Active) (ab259386)

    M-Arg + 0.3 Da (loss of C-terminal lysine during analysis). Calculated MW is 19175.70 Da.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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