Recombinant mouse IL-13 protein (Active) (ab270080)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 95% Immunogen affinity purified
- Endotoxin level:
- Active: Yes
- Suitable for: Cell Culture, Functional Studies, HPLC, MS, SDS-PAGE
Preparation and Storage
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Alternative names
- Allergic rhinitis
- ALRH
- BHR 1
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Function
Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages. -
Involvement in disease
Allergic rhinitis -
Sequence similarities
Belongs to the IL-4/IL-13 family. -
Cellular localization
Secreted. - Information by UniProt
Images
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Functional Studies - Recombinant mouse IL-13 protein (Active) (ab270080)
Fully biologically active when compared to standard. Determined by the dose dependant proliferation of TF-1 cell line.
ED50 is ≤ 1.892 ng/mL, corresponding to a specific activity of 5.29 x 105 units/mg.
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SDS-PAGE - Recombinant mouse IL-13 protein (Active) (ab270080)SDS-PAGE analysis of ab270080.The protein has multiple N-linked glycosylations. -
HPLC - Recombinant mouse IL-13 protein (Active) (ab270080)Purity by HPLC ≥95%.
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Mass Spectrometry - Recombinant mouse IL-13 protein (Active) (ab270080)M+1.63 Da, pass (+655 Da: Hex(1)HexNAc(1)NeuAc(1)). Calc MW 12409.37 Da