Recombinant Mouse DPP2 protein (His tag) (ab276965)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 92% SDS-PAGE
- Endotoxin level:
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Mouse DPP2 protein (His tag)
See all DPP2 proteins and peptides -
Purity
> 92 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Full length proteinAnimal free
NoNature
Recombinant-
Species
Mouse -
Sequence
MNFHPCYPVD HGVPSWILVL LLSLGLCNLQ ARADRVLDPD FHENYFEQYM DHFNFESFGN KTFGQRFLVS DKFWKMGEGP IFFYTGNEGD IWSFANNSGF MVELAAQQEA LLVFAEHRYY GKSLPFGVQS TQRGYTQLLT VEQALADFAV LLQALRQDLG VHDAPTIAFG GSYGGMLSAY MRMKYPHLVA GALAASAPVV AVAGLGDSYQ FFRDVTADFY GQSPKCAQAV RDAFQQIKDL FLQGAYDTIS QNFGTCQSLS SPKDLTQLFG FARNAFTVLA MMDYPYPTDF LGPLPANPVK VGCQRLLNEG QRIMGLRALA GLVYNSSGTE PCYDIYRLYQ SCADPTGCGT GSDARAWDYQ ACTEINLTFD SNNVTDMFPE IPFSEELRQQ YCLDTWGVWP RQDWLQTSFW GGDLKAASNI IFSNGDLDPW AGGGIQSNLS TSVIAVTIQG GAHHLDLRAS NSEDPPSVVE VRKLESTLIR EWVAAARLKQ PAMPRWPGPK KQHPSR -
Predicted molecular weight
54 kDa including tags -
Molecular weight information
The recombinant mouse DPP7 consists of 484 amino acids and predicts a molecular mass of 53.7 KDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmDPP7 is approximately 65 KDa as a result of glycosylation. -
Amino acids
1 to 506 -
Tags
His tag C-Terminus -
Additional sequence information
Predicted N-terminus: Asp 34.
Specifications
Our Abpromise guarantee covers the use of ab276965 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- Dipeptidyl aminopeptidase II
- Dipeptidyl peptidase 7
- Dipeptidyl peptidase II
see all -
Relevance
DPP2 is a serine protease found most abundantly in the lysosome. There is also a non-lysosomal membrane-associated form of DPP2 reported in the rat brain (DPP-II-M), and a soluble form (DPP-II-S). First discovered as an enzyme involved in the terminal steps of protein degradation, and later as an enzyme involved in cell growth and quiescence, DPP2 cleaves N-terminal dipeptides and tripeptides from proteins. DPP2 has a preference for proline in the P1 position, and processes the tripeptides generated by DPP1 (which is unable to cleave if proline is in the P1 position). Some tumor cell lines express elevated DPP2 levels, and serum levels of DPP2 are elevated in some cancer patients, making DPP2 a potential tumor marker. DPP2 levels have been also been reported to be elevated in the cerebral spinal fluid from Parkinson’s patients. -
Cellular localization
Lysosome. Cytoplasmic vesicle. Secreted.
Images
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SDS-PAGE - Recombinant Mouse DPP2 protein (ab276965)SDS-PAGE analysis of ab276965
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276965 has not yet been referenced specifically in any publications.
Preparation and Storage
- Dipeptidyl aminopeptidase II
- Dipeptidyl peptidase 7
- Dipeptidyl peptidase II
Images
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SDS-PAGE - Recombinant Mouse DPP2 protein (ab276965)SDS-PAGE analysis of ab276965