Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant mouse CCL21 protein (ab9904)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant mouse CCL21 protein
    See all CCL21 proteins and peptides

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    P86793

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      SDGGGQDCCLKYSQKKIPYSIVRGYRKQEPSLGCPIPAILFLPRKHSKPE LCANPEEGWVQNLMRRLDQPPAPGKQSPGCRKNRGTSKSGKKGKGSKGCK RTEQTQPSRG

    • Predicted molecular weight

      15 kDa

    • Amino acids

      24 to 133

    • Specifications

    Our Abpromise guarantee covers the use of ab9904 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      SDS-PAGE

    • Form

      Lyophilized

    • Additional notes

      The biological activity of this product was determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 10.0-100.0 ng/ml.

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      For lot specific reconstitution information please contact our Scientific Support Team.

    General Info

    • Alternative names

      • 6Ckine
      • Beta chemokine exodus 2
      • Beta-chemokine exodus-2
      • C C motif chemokine ligand 21
      • C-C motif chemokine 21
      • CCL21
      • CCL21_HUMAN
      • Chemokine (C-C motif) ligand 21
      • Chemokine CC motif ligand 21
      • CKb9
      • ECL
      • Efficient Chemoattractant for Lymphocytes
      • SCYA21
      • Secondary lymphoid tissue chemokine
      • Secondary lymphoid-tissue chemokine
      • SLC
      • Small inducible cytokine A21
      • Small inducible cytokine subfamily A (Cys-Cys), member 21
      • Small-inducible cytokine A21
      • TCA4
      • UNQ784/PRO1600
      see all

    • Function

      Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs.

    • Tissue specificity

      Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen.

    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.

    • Cellular localization

      Secreted.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (1)

Publishing research using ab9904? Please let us know so that we can cite the reference in this datasheet.

ab9904 has been referenced in 1 publication.

  • Caines R  et al. The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy. J Cell Sci 132:N/A (2019). PubMed: 31331967

Preparation and Storage

  • 6Ckine
  • Beta chemokine exodus 2
  • Beta-chemokine exodus-2

Images

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