Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human VSIG4 protein (Fc Chimera) (ab185422)

Key features and details

  • Expression system: Mammalian
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: HPLC, SDS-PAGE

Description

  • Product name

    Recombinant Human VSIG4 protein (Fc Chimera)
    See all VSIG4 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Purity is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

  • Expression system

    Mammalian

  • Accession

    Q9Y279

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      RPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTIFL RDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQT PDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARG SPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVGS EQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSWDWTTDMDG YLGETSAGPGKSLPVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFL FPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPR EEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQ PREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYK TTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLS LSPGK

    • Predicted molecular weight

      56 kDa including tags

    • Amino acids

      20 to 284

    • Additional sequence information

      Fused with a FC tag at the C-terminus.

    • Specifications

    Our Abpromise guarantee covers the use of ab185422 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      HPLC

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Reconstitute for long term storage.

      pH: 7.40
      Constituent: 99% PBS

    • Reconstitution
      Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    General Info

    • Alternative names

      • Complement receptor of the immunoglobulin superfamily
      • CRIg
      • Ig superfamily protein
      • Protein Z39Ig
      • UNQ317/PRO362
      • V set and immunoglobulin domain containing 4
      • V-set and immunoglobulin domain-containing protein 4
      • VSIG4
      • VSIG4_HUMAN
      • Z39IG
      see all

    • Function

      Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.

    • Tissue specificity

      Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta. Expressed in resting macrophages.

    • Sequence similarities

      Contains 2 Ig-like (immunoglobulin-like) domains.

    • Cellular localization

      Membrane.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab185422? Please let us know so that we can cite the reference in this datasheet.

ab185422 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Complement receptor of the immunoglobulin superfamily
  • CRIg
  • Ig superfamily protein

Images

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