Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human UCMA protein (ab185848)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human UCMA protein

  • Purity

    > 95 % SDS-PAGE.
    Assessed also by SEC-HPLC

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    Q8WVF2

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      GHMSPKSRDEVNVENRQKLRVDELRREYYEEQRNEFENFVEEQNDEQEER SREAVEQWRQWHYDG LHPSYLYNRHHT

    • Predicted molecular weight

      10 kDa

    • Amino acids

      65 to 138

    • Additional sequence information

      Unique cartilage matrix-associated protein C-terminal fragment

    • Specifications

    Our Abpromise guarantee covers the use of ab185848 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.2
      Constituent: 100% PBS

      Lyophilized from a 0.2 µM filtered solution

    General Info

    • Alternative names

      • 1110017I16Rik
      • AW121955
      • C10orf49
      • Gla rich protein
      • Gla-rich protein
      • GRP
      • OTTMUSP00000011599
      • RP23-272I15.1
      • UCMA
      • Ucma-C
      • UCMA_HUMAN
      • Unique cartilage matrix associated protein
      • Unique cartilage matrix-associated protein C-terminal fragment
      • Upper zone of growth plate and cartilage matrix associated
      see all

    • Function

      May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.

    • Tissue specificity

      Predominantly expressed in resting chondrocytes.

    • Sequence similarities

      Belongs to the UCMA family.

    • Post-translational
      modifications

      Proteolytically cleaved by a furin-like convertase to generate a persistent C-terminal fragment found in almost the entire cartilage matrix, and affecting osteoblast differentiation.
      Sulfated on tyrosine residues.

    • Cellular localization

      Secreted > extracellular space > extracellular matrix.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab185848? Please let us know so that we can cite the reference in this datasheet.

ab185848 has not yet been referenced specifically in any publications.

Preparation and Storage

  • 1110017I16Rik
  • AW121955
  • C10orf49

Images

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