Recombinant human TYRO3 protein (Active) (ab271778)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: >= 55% SDS-PAGE
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
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Product name
Recombinant human TYRO3 protein (Active)
See all TYRO3 proteins and peptides -
Biological activity
Specific Activity: 140 nmol/min/mg.
Assay Conditions: Assay was done in Kinase buffer containing 2 mM DTT using Poly-(Glu4:Tyr) substrate (0.2 mg/ml) and 20 μM ATP. Reaction was performed at 30°C for 45 min. Amount of ATP transferred was calculated using Kinase-Glo reagent.
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Purity
>= 55 % SDS-PAGE. -
Expression system
Baculovirus infected Sf9 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
RKETRFGQAFDSVMARGEPAVHFRAARSFNRERPERIEATLDSLGISDEL KEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKA DIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILP FMKHGDLHAFLLASRIGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHR DLAARNCMLAEDMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESL ADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQP PECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQLSVLSASQDPLY INIERAEEPTAGGSLELPGRDQPYSGAGDGSGMGAVGGTPSDCRYILTPG GLAEQPGQAEHQPESPLNETQRLLLLQQGLLPHSSC -
Predicted molecular weight
77 kDa including tags -
Amino acids
455 to 890 -
Tags
GST tag N-Terminus
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Preparation and Storage
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Alternative names
- Brt
- BYK
- DTK
see all -
Function
May be involved in cell adhesion processes, particularly in the central nervous system. In case of filovirus infection, seems to function as a cell entry factor. -
Tissue specificity
Abundant in the brain and lower levels in other tissues. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
Contains 2 fibronectin type-III domains.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
Cellular localization
Cell membrane. - Information by UniProt
Images
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Functional Studies - Recombinant human TYRO3 protein (Active) (ab271778)
Specific activity of ab271778 was 140 nmol/min/mg in a kinase assay using Poly-(Glu4:Tyr) as substrate.
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SDS-PAGE - Recombinant human TYRO3 protein (Active) (ab271778)SDS-PAGE analysis of ab271778.