Recombinant human TNFRSF14/HVEM protein (Biotin) (ab198632)
Key features and details
- Expression system: HEK 293 cells
- Endotoxin level:
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
Preparation and Storage
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Alternative names
- HVEML
- ATAR
- CD270
see all -
Function
Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. -
Tissue specificity
Widely expressed, with the highest expression in lung, spleen and thymus. -
Sequence similarities
Contains 3 TNFR-Cys repeats. -
Post-translational
modificationsN-glycosylated. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant human TNFRSF14/HVEM protein (Biotin) (ab198632)
4-20% SDS-PAGE with Coomassie stain
Lane 1: 2 µg ab198632
Lane 2: Protein marker -
Functional Studies - Recombinant human TNFRSF14/HVEM protein (Biotin) (ab198632)BTLA:TNFRSF14/HVEM binding activity, measured using an Inhibitor Screening Assay Kit.
