Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human TIL/TLR1 protein (ab157264)

Key features and details

  • Expression system: NSO cells
  • Purity: > 90% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human TIL/TLR1 protein

  • Purity

    > 90 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    NSO cells

  • Accession

    Q15399

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      SEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISELWTSDILSLSKLRIL IISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLDLSFN AFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGET YGEKEDPEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCV LEDNKCSYFLSILAKLQTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVW YFSISNVKLQGQLDFRDFDYSGTSLKALSIHQVVSDVFGFPQSYIYEIFS NMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLLTDTVFENCGHLTEL ETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCSWTKS LLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELN VAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDN PFQCTCELGEFVKNIDQVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSE LSCNIT

    • Predicted molecular weight

      120 kDa

    • Amino acids

      25 to 580

    • Associated products

    Specifications

    Our Abpromise guarantee covers the use of ab157264 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20ºC.

      Constituent: 99% PBS

    • Reconstitution
      Reconstitute in 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

    General Info

    • Alternative names

      • CD281
      • CD281 antigen
      • KIAA0012
      • LPRS5
      • rsc786
      • TIL
      • TIL. LPRS5
      • Tlr1
      • TLR1_HUMAN
      • Toll (Drosophila) homolog
      • Toll like receptor 1
      • Toll-like receptor 1
      • Toll/interleukin-1 receptor-like protein
      see all

    • Function

      Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

    • Tissue specificity

      Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.

    • Sequence similarities

      Belongs to the Toll-like receptor family.
      Contains 12 LRR (leucine-rich) repeats.
      Contains 1 LRRCT domain.
      Contains 1 TIR domain.

    • Cellular localization

      Cell membrane. Cytoplasmic vesicle > phagosome membrane.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab157264? Please let us know so that we can cite the reference in this datasheet.

ab157264 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituent: 99% PBS

  • Reconstitution
    Reconstitute in 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Images

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