Recombinant Human TIA1 protein (ab131879)
Key features and details
- Expression system: Wheat germ
- Suitable for: WB, SDS-PAGE, ELISA
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Product name
Recombinant Human TIA1 protein -
Expression system
Wheat germ -
Accession
-
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCF VEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQ RSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYG FVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYECRCIGE EKEMWNFGEKYARF -
Predicted molecular weight
49 kDa including tags -
Amino acids
1 to 214
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Preparation and Storage
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Alternative names
- Cytotoxic granule associated RNA binding protein
- Cytotoxic granule associated RNA binding protein 1
- mTIA-1
see all -
Function
Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. -
Sequence similarities
Contains 3 RRM (RNA recognition motif) domains. -
Cellular localization
Cytoplasmic granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human TIA1 protein (ab131879)12.5% SDS-PAGE stained with Coomassie Blue showing ab131879 at approximately 49.28 kDa.
