Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human Thimet Oligopeptidase protein (ab151886)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: HPLC, SDS-PAGE

Description

  • Product name

    Recombinant Human Thimet Oligopeptidase protein

  • Purity

    > 95 % SDS-PAGE.
    Purity is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. ab151886 is supplied as a 0.2 µm filtered solution.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    P52888

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      KPPAACAGDMADAASPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQV GTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEA DKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERLIKLGRR NGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPE DFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEE NCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQK LKPLGEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCV DQNLLKEYFPVQVVTHGLLGIYQELLGLAFHHEEGASAWHEDVRLYTARD AASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSRQIAIAAMVAN FTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFV EAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFN LRQIVLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHL AGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGS EDASAMLRRFLGRDPKQDAFLLSKGLQVGGCEPEPQVC

    • Predicted molecular weight

      79 kDa

    • Amino acids

      2 to 689

    • Specifications

    Our Abpromise guarantee covers the use of ab151886 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      HPLC

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 7.00
      Constituents: 89% Phosphate Buffer, 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride

    General Info

    • Alternative names

      • EC 3.4.24.15
      • Endopeptidase 24.15
      • EP24.15
      • MEPD_HUMAN
      • MP78
      • Thimet oligopeptidase
      • Thimet oligopeptidase 1
      • Thop1
      • THOP1_HUMAN
      • TOP
      see all

    • Function

      Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.

    • Sequence similarities

      Belongs to the peptidase M3 family.

    • Cellular localization

      Cytoplasm.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab151886? Please let us know so that we can cite the reference in this datasheet.

ab151886 has not yet been referenced specifically in any publications.

Preparation and Storage

  • EC 3.4.24.15
  • Endopeptidase 24.15
  • EP24.15

Images

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