Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human TARC/CCL17 protein (ab9817)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: SDS-PAGE, Functional Studies

Description

  • Product name

    Recombinant human TARC/CCL17 protein
    See all TARC/CCL17 proteins and peptides

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Predicted molecular weight

      11 kDa

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab9817 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        Functional Studies

      • Form

        Lyophilized

      • Additional notes

        The biological activity of this product is determined by its ability to chemoattract human T-lymphocytes using a concentration range of 1.0-10.0 ng/ml.

         This product was previously labelled as TARC

         

      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        Please reconstitute this product in 200ul water.

      General Info

      • Alternative names

        • A-152E5.3
        • A152E53
        • ABCD 2
        • ABCD2
        • C-C motif chemokine 17
        • CC chemokine TARC
        • CCL17
        • CCL17_HUMAN
        • Chemokine CC Motif Ligand 17
        • MGC138271
        • MGC138273
        • SCYA17
        • Small Inducible Cytokine A17
        • Small Inducible Cytokine A17 Precursor
        • Small Inducible Cytokine Subfamily A (Cys Cys)
        • Small Inducible Cytokine Subfamily A (Cys Cys) Member 17
        • Small-inducible cytokine A17
        • T Cell Directed CC Chemokine
        • Thymus and activation regulated chemokine
        • Thymus and activation-regulated chemokine
        see all

      • Function

        Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.

      • Tissue specificity

        Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.

      • Sequence similarities

        Belongs to the intercrine beta (chemokine CC) family.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (1)

    Publishing research using ab9817? Please let us know so that we can cite the reference in this datasheet.

    ab9817 has been referenced in 1 publication.

    • Goldie SJ  et al. Loss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis. Cell Death Dis 9:1072 (2018). PubMed: 30341279

    Preparation and Storage

    • Alternative names

      • A-152E5.3
      • A152E53
      • ABCD 2
      • ABCD2
      • C-C motif chemokine 17
      • CC chemokine TARC
      • CCL17
      • CCL17_HUMAN
      • Chemokine CC Motif Ligand 17
      • MGC138271
      • MGC138273
      • SCYA17
      • Small Inducible Cytokine A17
      • Small Inducible Cytokine A17 Precursor
      • Small Inducible Cytokine Subfamily A (Cys Cys)
      • Small Inducible Cytokine Subfamily A (Cys Cys) Member 17
      • Small-inducible cytokine A17
      • T Cell Directed CC Chemokine
      • Thymus and activation regulated chemokine
      • Thymus and activation-regulated chemokine
      see all

    • Function

      Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.

    • Tissue specificity

      Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.

    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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