Recombinant Human Statherin protein (Fc Chimera) (ab276578)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Tags: Fc tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human Statherin protein (Fc Chimera) -
Purity
> 95 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Full length proteinAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
MKFLVFAFIL ALMVSMIGAD SSEEKFLRRI GRFGYGYGPY QPVPEQPLYP QPYQPQYQQY TF -
Predicted molecular weight
32 kDa including tags -
Molecular weight information
The recombinant human STATH/mFc is a disulfide-linked homodimer. The reduced monomer comprises 277 amino acids and has a predicted molecular mass of 31.6 kDa. The apparent molecular mass of the protein is approximately 36 in SDS-PAGE under reducing conditions. -
Amino acids
1 to 62 -
Tags
Fc tag C-Terminus -
Additional sequence information
Fc region of mouse IgG1. Predicted N-terminus: Asp 20.
Specifications
Our Abpromise guarantee covers the use of ab276578 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.4
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- STAT_HUMAN
- STATH
- Statherin
see all -
Function
Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts. It also modulates hydroxyapatite crystal formation on the tooth surface. -
Tissue specificity
Secreted by parotid and submandibular glands. -
Sequence similarities
Belongs to the histatin/statherin family. -
Post-translational
modificationsSubstrate for transglutaminase-2. More than 95% of the cyclized peptide is cyclo-statherin Q-37, and less than 5% is cyclo-statherin Q-39. Cyclized forms account for about 1% of total statherin in saliva.
Sulfated on tyrosine residues. -
Cellular localization
Secreted. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human Statherin protein (ab276578)SDS-PAGE analysis of ab276578
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276578 has not yet been referenced specifically in any publications.
Preparation and Storage
- STAT_HUMAN
- STATH
- Statherin
Images
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SDS-PAGE - Recombinant Human Statherin protein (ab276578)SDS-PAGE analysis of ab276578