Recombinant Human SLAMF7/CS1 protein (Fc Chimera) (ab276423)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 90% SDS-PAGE
- Endotoxin level:
- Tags: Fc tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human SLAMF7/CS1 protein (Fc Chimera)
See all SLAMF7/CS1 proteins and peptides -
Purity
> 90 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Protein fragmentAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
MAGSPTCLTL IYILWQLTGS AASGPVKELV GSVGGAVTFP LKSKVKQVDS IVWTFNTTPL VTIQPEGGTI IVTQNRNRER VDFPDGGYSL KLSKLKKNDS GIYYVGIYSS SLQQPSTQEY VLHVYEHLSK PKVTMGLQSN KNGTCVTNLT CCMEHGEEDV IYTWKALGQA ANESHNGSIL PISWRWGESD MTFICVARNP VSRNFSSPIL ARKLCEGAAD DPDSSM -
Predicted molecular weight
49 kDa including tags -
Molecular weight information
The recombinant human SLAMF7 consists of 442 amino acids and predicts a molecular mass of 49.1 kDa. -
Amino acids
1 to 226 -
Tags
Fc tag C-Terminus -
Additional sequence information
Fc region of human IgG1.Predicted N-terminus: Ser 23.
Specifications
Our Abpromise guarantee covers the use of ab276423 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- 19A
- 19A24 protein
- CD 319
see all -
Relevance
SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms. -
Cellular localization
Membrane; Single-pass type I membrane protein.
Images
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SDS-PAGE - Recombinant Human SLAMF7/CS1 protein (ab276423)
SDS-PAGE analysis of ab276423.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276423 has not yet been referenced specifically in any publications.
Preparation and Storage
- 19A
- 19A24 protein
- CD 319
Images
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SDS-PAGE - Recombinant Human SLAMF7/CS1 protein (ab276423)
SDS-PAGE analysis of ab276423.