Recombinant Human RSPO2 protein (Fc Chimera) (ab276499)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 90% SDS-PAGE
- Endotoxin level:
- Tags: Fc tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human RSPO2 protein (Fc Chimera)
See all RSPO2 proteins and peptides -
Purity
> 90 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Protein fragmentAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
MQFRLFSFAL IILNCMDYSH CQGNRWRRSK RASYVSNPIC KGCLSCSKDN GCSRCQQKLF FFLRREGMRQ YGECLHSCPS GYYGHRAPDM NRCARCRIEN CDSCFSKDFC TKCKVGFYLH RGRCFDECPD GFAPLEETME CVEGCEVGHW SEWGTCSRNN RTCGFKWGLE TRTRQIVKKP VKDTILCPTI AESRRCKMTM RHCPG -
Predicted molecular weight
48 kDa including tags -
Molecular weight information
The secreted recombinant human RSPO2/Fc is a disulfide-linked homodimer. The reduced monomer comprises 425 amino acids and has a predicted molecular mass of 48.3 kDa. ?The apparent molecular mass of rh RSPO2/Fc monomer is approximately 50 kDa in SDS-PAGE under reducing conditions. -
Amino acids
1 to 205 -
Modifications
mutated L186P -
Tags
Fc tag C-Terminus -
Additional sequence information
Fc region of human IgG1.Predicted N-terminus: Gln 22.
Specifications
Our Abpromise guarantee covers the use of ab276499 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- CRISTIN2
- hRspo2
- R spondin 2
see all -
Relevance
RSPO2 is part of the R-spondin family of proteins that consist of secreted cysteine-rich proteins that can activate beta-catenin signaling via the Frizzled/LRP5/6 receptor complex. R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis. RSPO2 expression in required in the apical ectodermal ridge for normal hindlimb development. -
Cellular localization
Secreted
Images
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SDS-PAGE - Recombinant Human RSPO2 protein (ab276499)SDS-PAGE analysis of ab276499
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276499 has not yet been referenced specifically in any publications.
Preparation and Storage
- CRISTIN2
- hRspo2
- R spondin 2
Images
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SDS-PAGE - Recombinant Human RSPO2 protein (ab276499)SDS-PAGE analysis of ab276499