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Signal Transduction Growth Factors/Hormones Insulin / Insulin-like

Recombinant Human Relaxin 2/RLN2 protein (ab63227)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human Relaxin 2/RLN2 protein
    See all Relaxin 2/RLN2 proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    Purity: >98%, assessed by SDS Page and HPLC analysis. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    P04090
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      A-Chain: QLYSALANKC CHVGCTKRSL ARFC B-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS
    • Additional sequence information

      B chain = aa 26-53 A chain = aa 162-185
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab63227 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

      • Form

        Lyophilized
      • Additional notes

        This product was previously labelled as Relaxin 2

         

      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Upon delivery aliquot. Upon reconsitution add a carrier protein (0.1% BSA). Store at -20°C. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C..

      • Reconstitution
        Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex.

      General Info

      • Alternative names

        • H2
        • REL2_HUMAN
        • Relaxin 2
        • Relaxin A chain
        • Relaxin H2
        • RLN2
        • RLXH2
        see all
      • Function

        Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
      • Tissue specificity

        Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary.
      • Sequence similarities

        Belongs to the insulin family.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession P04090 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab63227? Please let us know so that we can cite the reference in this datasheet.

    ab63227 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • H2
      • REL2_HUMAN
      • Relaxin 2
      • Relaxin A chain
      • Relaxin H2
      • RLN2
      • RLXH2
      see all
    • Function

      Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
    • Tissue specificity

      Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary.
    • Sequence similarities

      Belongs to the insulin family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P04090 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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