Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human Profilin 2 protein (ab185845)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human Profilin 2 protein
    See all Profilin 2 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Purity is determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    P35080

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDM IVGKDREGFFTNGLALGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYN VAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF

    • Predicted molecular weight

      15 kDa

    • Amino acids

      1 to 140

    • Associated products

    Specifications

    Our Abpromise guarantee covers the use of ab185845 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.24% Tris, 0.88% Sodium chloride

      Lyophilized from a 0.2 µM filtered solution

    General Info

    • Alternative names

      • D3S1319E
      • PFL
      • PFN 2
      • Pfn2
      • PROF2_HUMAN
      • Profilin II
      • Profilin-2
      • Profilin2
      • ProfilinII
      see all

    • Function

      Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

    • Tissue specificity

      Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.

    • Sequence similarities

      Belongs to the profilin family.

    • Cellular localization

      Cytoplasm > cytoskeleton.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab185845? Please let us know so that we can cite the reference in this datasheet.

ab185845 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.24% Tris, 0.88% Sodium chloride

    Lyophilized from a 0.2 µM filtered solution

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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