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Recombinant Human NrCAM protein (ab191986)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human NrCAM protein

  • Purity

    > 95 % SDS-PAGE.
    Purity greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q92823-3

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      QMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKP PPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCT ARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLP PPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNH TQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECI AEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK NALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRIS WLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLA NAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAK GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK DATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDER FTVDKDHLVVADVSDDDSGTYTCVANVDDIEGRMDEPKSCDKTHTCPPCP APELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVD GVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPA PIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVE WESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHE ALHNHYTQKSLSLSPGK

    • Predicted molecular weight

      91 kDa including tags

    • Amino acids

      25 to 600

    • Additional sequence information

      Fused with a FC tag at the C-terminus.

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab191986 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        HPLC

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        pH: 7.40
        Constituent: 100% PBS

        Lyophilized from a 0.2 µM filtered solution.

      • Reconstitution
        Dissolve protein in 1 x PBS to a concentration no less than 100ug/ml.

      General Info

      • Alternative names

        • Bravo
        • hBravo
        • Neuronal cell adhesion molecule
        • Neuronal surface protein Bravo
        • Ng CAM related
        • Ng-CAM-related
        • NgCAM related cell adhesion molecule
        • NgCAM-related cell adhesion molecule
        • Nr CAM
        • Nr-CAM
        • Nrcam
        • NRCAM_HUMAN
        see all

      • Function

        Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier.

      • Tissue specificity

        Detected in all the examined tissues. In the brain it was detected in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.

      • Sequence similarities

        Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
        Contains 5 fibronectin type-III domains.
        Contains 6 Ig-like C2-type (immunoglobulin-like) domains.

      • Cellular localization

        Cell membrane.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab191986? Please let us know so that we can cite the reference in this datasheet.

    ab191986 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • Bravo
      • hBravo
      • Neuronal cell adhesion molecule
      • Neuronal surface protein Bravo
      • Ng CAM related
      • Ng-CAM-related
      • NgCAM related cell adhesion molecule
      • NgCAM-related cell adhesion molecule
      • Nr CAM
      • Nr-CAM
      • Nrcam
      • NRCAM_HUMAN
      see all

    • Function

      Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier.

    • Tissue specificity

      Detected in all the examined tissues. In the brain it was detected in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.

    • Sequence similarities

      Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
      Contains 5 fibronectin type-III domains.
      Contains 6 Ig-like C2-type (immunoglobulin-like) domains.

    • Cellular localization

      Cell membrane.
    • Information by UniProt

    Images

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