Recombinant Human Leptin protein (Active) (ab269249)
Key features and details
- Expression system: Escherichia coli
- Endotoxin level:
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Preparation and Storage
-
Alternative names
- FLJ94114
- LEP
- LEP_HUMAN
see all -
Function
May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. -
Involvement in disease
Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. -
Sequence similarities
Belongs to the leptin family. -
Cellular localization
Secreted. - Information by UniProt
Images
-
SDS-PAGE - Recombinant Human Leptin protein (ab269249)
SDS-PAGE analysis of ab269249 at 1ug/lane under non-reducing conditions. 4-20% Tris glycine gel. Stained with coomassie blue.
-
Functional Studies - Recombinant Human Leptin protein (Active) (ab269249)Biological activity graph of ab269249