Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human LEC protein (ab202776)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 97% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE, HPLC

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 99% Phosphate Buffer, 0.87% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Briefly centrifuge prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at

    General Info

    • Alternative names

      • C-C motif chemokine 16
      • CCL16
      • CCL16_HUMAN
      • Chemokine (C-C motif) ligand 16
      • Chemokine CC-4
      • Chemokine LEC
      • CKb12
      • HCC-4
      • HCC4
      • IL-10-inducible chemokine
      • IL10 inducible chemokine
      • ILINCK
      • LCC-1
      • LCC1
      • Liver CC chemokine 1 precursor
      • Liver expressed chemokine
      • Liver-expressed chemokine
      • LMC
      • Lymphocyte and monocyte chemoattractant
      • Monotactin 1
      • Monotactin-1
      • MTN-1
      • Mtn1
      • NCC-4
      • NCC4
      • New CC chemokine 4
      • SCYA16
      • SCYL4
      • Small inducible cytokine A16 precursor
      • Small inducible cytokine subfamily A (Cys Cys) member 16
      • Small-inducible cytokine A16
      see all

    • Function

      Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.

    • Tissue specificity

      Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.

    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

References (0)

Publishing research using ab202776? Please let us know so that we can cite the reference in this datasheet.

ab202776 has not yet been referenced specifically in any publications.

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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