Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human ketohexokinase protein (ab191946)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: HPLC, SDS-PAGE

Description

  • Product name

    Recombinant Human ketohexokinase protein
    See all ketohexokinase proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Purity greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. ab191946 is supplied as a 0.2 µM filtered solution.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    P50053

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTIL SLLGAPCAFMGSMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVI INEASGSRTILYYDRSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKML QRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLG FQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRV VDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIVVD HHHHHH

    • Predicted molecular weight

      34 kDa

    • Amino acids

      1 to 298

    • Tags

      His tag C-Terminus

    • Specifications

    Our Abpromise guarantee covers the use of ab191946 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      HPLC

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 0.32% Tris HCl, 10% Glycerol (glycerin, glycerine), 0.38% Potassium chloride

      0.2 µM filtered solution

    General Info

    • Alternative names

      • EC 2.7.1.3
      • Fructokinase
      • Hepatic fructokinase
      • Ketohexokinase
      • Ketohexokinase isoform a
      • KHK
      • KHK_HUMAN
      see all

    • Tissue specificity

      Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.

    • Pathway

      Carbohydrate metabolism; fructose metabolism.

    • Involvement in disease

      Defects in KHK are the cause of fructosuria (FRUCT) [MIM:229800]. Fructosuria is a benign defect of intermediary metabolism.

    • Sequence similarities

      Belongs to the carbohydrate kinase pfkB family.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab191946? Please let us know so that we can cite the reference in this datasheet.

ab191946 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 0.32% Tris HCl, 10% Glycerol (glycerin, glycerine), 0.38% Potassium chloride

    0.2 µM filtered solution

Images

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