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Recombinant Human ITIH3 protein (ab194042)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

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Description

  • Product name

    Recombinant Human ITIH3 protein
  • Purity

    > 95 % SDS-PAGE.
    The purity of ab194042 was determined by SEC-HPLC and reducing SDS-PAGE.
  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    Q06033
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      LPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELP KTAFITNFTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRK LEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEI EVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQR SCPTCTDSLLNGDFTITYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKN VAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKE HLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPE RSTSIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYN FLENMALENHGFARRIYEDSDADLQLQGFYEEVANPLLTGVEMEYPENAI LDLTQNTYQHFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEV DMKEMEKALQERDYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTAR ALDLSLKYHFVTPLTSMVVTKPEDNEDERAIADKPGEDAEATPVSPAMSY LTSYQPPQNPYYYVDGDVDHHHHHH
    • Predicted molecular weight

      70 kDa including tags
    • Amino acids

      35 to 651
    • Tags

      His tag C-Terminus
    • Additional sequence information

      This product is for the mature full length protein from aa 35 to 651. The signal and propeptide peptides are not included.
  • Associated products

    • Related Products

      • Anti-6X His tag® antibody [HIS.H8] (ab18184)
      • Anti-6X His tag® antibody [4D11] (ab5000)
      • Anti-6X His tag® antibody (ab9108)
      • Anti-ITIH3 antibody (ab97758)

    Specifications

    Our Abpromise guarantee covers the use of ab194042 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 99% Phosphate Buffer, 0.87% Sodium chloride

      Lyophilized from a 0.2 µM filtered solution.

    General Info

    • Alternative names

      • AW108094
      • H3P
      • Inter alpha (globulin) inhibitor, H3 polypeptide
      • Inter alpha inhibitor heavy chain 3
      • Inter alpha trypsin inhibitor heavy chain H3
      • Intin3
      • ITI HC3
      • ITI heavy chain H3
      • PAIHC3
      • Pre alpha-inhibitor, heavy chain 3
      • Serum derived hyaluronan-associated protein
      • SHAP
      see all
    • Relevance

      The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. ITIH3 may act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
    • Cellular localization

      Secreted

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab194042? Please let us know so that we can cite the reference in this datasheet.

    ab194042 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 99% Phosphate Buffer, 0.87% Sodium chloride

      Lyophilized from a 0.2 µM filtered solution.

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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