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Cancer Tumor immunology Cytokines Interleukins

Recombinant human IL-29 protein (ab200263)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 97% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE, HPLC

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Description

  • Product name

    Recombinant human IL-29 protein
    See all IL-29 proteins and peptides
  • Biological activity

    Fully biologically active when compared to standard. The ED50 is determined in an anti-viral assay using Human HepG2 cells infected with encephalomyocarditis is typically 1-5 ng/ml.

  • Purity

    > 97 % SDS-PAGE.
    ab200263 is >97% pure as determined by SDS-PAGE and HPLC analyses.
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    Q8IU54
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      PTSKPTTTGKGCHIGRFKSLSPQELASFKKARDALEESLKLKNWSCSSPV FPGNWDLRLLQVRERPVALEAELALTLKVLEAAAGPALEDVLDQPLHTLH HILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFN LFRLLTRDLKYVADGNLCLRTSTHPEST
    • Predicted molecular weight

      20 kDa
    • Amino acids

      23 to 200
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab200263 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

        HPLC

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at -20°C.

        pH: 7.40
        Constituents: 0.75% Sodium chloride, 99% Phosphate Buffer

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.

      General Info

      • Alternative names

        • Cytokine ZCYTO21
        • IFN lambda 1
        • IFN-lambda-1
        • IFNL1
        • IL-29
        • IL29
        • IL29_HUMAN
        • Interferon lambda 1
        • Interferon lambda-1
        • Interleukin 29 (interferon, lambda 1)
        • Interleukin-29
        see all
      • Function

        Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
      • Sequence similarities

        Belongs to the IL-28/IL-29 family.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession Q8IU54 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab200263? Please let us know so that we can cite the reference in this datasheet.

    ab200263 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • Cytokine ZCYTO21
      • IFN lambda 1
      • IFN-lambda-1
      • IFNL1
      • IL-29
      • IL29
      • IL29_HUMAN
      • Interferon lambda 1
      • Interferon lambda-1
      • Interleukin 29 (interferon, lambda 1)
      • Interleukin-29
      see all
    • Function

      Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
    • Sequence similarities

      Belongs to the IL-28/IL-29 family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession Q8IU54 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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