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Cancer Tumor immunology Cytokines Interleukins

Recombinant Human IL-28A protein (ab268668)

Recombinant Human IL-28A protein (ab268668)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human IL-28A protein
    See all IL-28A proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    Q8IZJ0
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      22 kDa
    • Actual molecular weight

      20 kDa
    • Additional sequence information

      Mature chain.
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab268668 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        pH: 7
        Constituent: PBS

        Lyophilized from a 0.2 micron filtered solution.

      • Reconstitution
        A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

      General Info

      • Alternative names

        • Cytokine ZCYTO20
        • IFN-lambda-2
        • IFNL2
        • IL-28A
        • IL28A
        • IL28A_HUMAN
        • Interferon lambda 2
        • Interferon lambda-2
        • Interleukin 28A
        • interleukin 28A (interferon, lambda 2)
        • Interleukin-28A
        • ZCYTO20
        see all
      • Function

        Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
      • Sequence similarities

        Belongs to the IL-28/IL-29 family.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession Q8IZJ0 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human IL-28A protein (ab268668)
      SDS-PAGE - Recombinant Human IL-28A protein (ab268668)

      ab268668 resolved on a 15% SDS-PAGE gel under reducing conditions.

      Stained with coomassie blue.

      MW ~19.5 kDa.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab268668? Please let us know so that we can cite the reference in this datasheet.

    ab268668 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • Cytokine ZCYTO20
      • IFN-lambda-2
      • IFNL2
      • IL-28A
      • IL28A
      • IL28A_HUMAN
      • Interferon lambda 2
      • Interferon lambda-2
      • Interleukin 28A
      • interleukin 28A (interferon, lambda 2)
      • Interleukin-28A
      • ZCYTO20
      see all
    • Function

      Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
    • Sequence similarities

      Belongs to the IL-28/IL-29 family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession Q8IZJ0 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human IL-28A protein (ab268668)
      SDS-PAGE - Recombinant Human IL-28A protein (ab268668)

      ab268668 resolved on a 15% SDS-PAGE gel under reducing conditions.

      Stained with coomassie blue.

      MW ~19.5 kDa.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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