Recombinant human IL-25 protein (Animal Free) (ab217425)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: HPLC, Functional Studies, SDS-PAGE
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Product name
Recombinant human IL-25 protein (Animal Free)
See all IL-25 proteins and peptides -
Biological activity
Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10-100 ng.
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Purity
> 98 % SDS-PAGE.
Assessed also by HPLC. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
Yes -
Nature
Recombinant -
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Species
Human -
Sequence
MYSHWPSCCP SKGQDTSEEL LRWSTVPVPP LEPARPNRHP ESCRASEDGP LNSRAISPWR YELDRDLNRL PQDLYHARCL CPHCVSLQTG SHMDPRGNSE LLYHNQTVFY RRPCHGEKGT HKGYCLERRL YRVSLACVCV RPRVMG -
Predicted molecular weight
34 kDa -
Amino acids
33 to 177 -
Additional sequence information
Mature full length chain without signal peptide. Homodimer of two 146 amino acid polypeptide chains.
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Preparation and Storage
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Alternative names
- IL 17E
- IL 25
- IL-17E
see all -
Function
Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses. -
Tissue specificity
Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea. -
Sequence similarities
Belongs to the IL-17 family. -
Cellular localization
Secreted. - Information by UniProt
