Recombinant Human IL-18R1 protein (ab200494)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Suitable for: SDS-PAGE
Preparation and Storage
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Alternative names
- CD218 antigen-like family member A
- CD218a
- CDw218a
see all -
Function
Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B. -
Tissue specificity
Expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression in Hodgkin disease cell lines. -
Sequence similarities
Belongs to the interleukin-1 receptor family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human IL-18R1 protein (ab200494)
SDS-PAGE analysis of DTT-reduced ab200494 stained overnight with Coomassie Blue. As a result of glycosylation, DTT-reduced protein migrates as 90-110 kDa.