Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human IL-18BP (ab193078)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human IL-18BP
    See all IL-18BP proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Purity greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    O95998

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      TPVSQTTTAATASVRSTKDPCPSQPPVFPAAKQCPALEVTWPEVEVPLNG TLSLSCVACSRFPNFSILYWLGNGSFIEHLPGRLWEGSTSRERGSTGTQL CKALVLEQLTPALHSTNFSCVLVDPEQVVQRHVVLAQLWAGLRATLPPTQ EALPSSHSSPQQQGVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFL FPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPR EEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQ PREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYK TTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLS LSPGK

    • Predicted molecular weight

      45 kDa including tags

    • Amino acids

      31 to 194

    • Additional sequence information

      This product is the mature full length protein from aa 31 to 194. The signal peptide is not included. Fused with an Fc tag at the C terminus.

  • Description

    Recombinant Human IL-18BP protein

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab193078 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        HPLC

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        pH: 7.40
        Constituent: 100% PBS

        Lyophilized from a 0.2 µM filtered solution.

      • Reconstitution
        Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

      General Info

      • Alternative names

        • I18BP_HUMAN
        • IL-18BP
        • IL18 binding protein
        • IL18 BP
        • IL18 BPa
        • IL18BP
        • IL18BPa
        • Interleukin 18 binding protein
        • Interleukin-18-binding protein
        • MC51L 53L 54L homolog gene product
        • Tadekinig alfa
        • Tadekinig-alfa
        see all

      • Function

        Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.

      • Tissue specificity

        Strongly expressed in heart, lung, placenta and spleen.

      • Sequence similarities

        Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab193078? Please let us know so that we can cite the reference in this datasheet.

    ab193078 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • I18BP_HUMAN
      • IL-18BP
      • IL18 binding protein
      • IL18 BP
      • IL18 BPa
      • IL18BP
      • IL18BPa
      • Interleukin 18 binding protein
      • Interleukin-18-binding protein
      • MC51L 53L 54L homolog gene product
      • Tadekinig alfa
      • Tadekinig-alfa
      see all

    • Function

      Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.

    • Tissue specificity

      Strongly expressed in heart, lung, placenta and spleen.

    • Sequence similarities

      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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