Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human IL-10 protein (Fc Chimera) (ab214119)

Key features and details

  • Expression system: CHO cells
  • Purity: > 98% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human IL-10 protein (Fc Chimera)
    See all IL-10 proteins and peptides

  • Purity

    > 98 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    CHO cells

  • Accession

    P22301

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      SPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQLDNLLLKE SLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKT LRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYI EAYMTMKIRN

    • Predicted molecular weight

      19 kDa

    • Amino acids

      19 to 178

    • Additional sequence information

      Mature extracellular form, without signal peptide, fused to the N-terminus of the Fc region of human IgG1.

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab214119 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

        Constituent: PBS

        Lyophilized from 0.2µm-filtered solution

      • Reconstitution
        Reconstitute with 100 µL sterile water. Add 1X PBS to the desired protein concentration. Working aliquots are stable for up to 3 months when stored at -20°C.

      General Info

      • Alternative names

        • CSIF
        • Cytokine synthesis inhibitory factor
        • GVHDS
        • IL 10
        • IL-10
        • IL10
        • IL10_HUMAN
        • IL10A
        • Interleukin 10
        • Interleukin-10
        • MGC126450
        • MGC126451
        • T-cell growth inhibitory factor
        • TGIF
        see all

      • Function

        Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.

      • Tissue specificity

        Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.

      • Sequence similarities

        Belongs to the IL-10 family.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab214119? Please let us know so that we can cite the reference in this datasheet.

    ab214119 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • CSIF
      • Cytokine synthesis inhibitory factor
      • GVHDS
      • IL 10
      • IL-10
      • IL10
      • IL10_HUMAN
      • IL10A
      • Interleukin 10
      • Interleukin-10
      • MGC126450
      • MGC126451
      • T-cell growth inhibitory factor
      • TGIF
      see all

    • Function

      Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.

    • Tissue specificity

      Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.

    • Sequence similarities

      Belongs to the IL-10 family.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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