Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human IGFBP2 protein (ab63223)

Key features and details

  • Expression system: Insect cells
  • Purity: > 98% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: WB, Functional Studies, SDS-PAGE

Preparation and Storage

  • Alternative names

    • BP 2
    • BP2
    • IBP 2
    • IBP-2
    • IBP2
    • IBP2_HUMAN
    • IGF binding protein 2
    • IGF BP53
    • IGF-binding protein 2
    • IGFBP 2
    • IGFBP-2
    • IGFBP2
    • IGFBP53
    • Insulin like growth factor binding protein 2
    • Insulin like growth factor binding protein 2 36kDa
    • Insulin like growth factor-binding protein 2 precursor
    • Insulin-like growth factor-binding protein 2
    see all

  • Function

    Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

  • Sequence similarities

    Contains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.

  • Domain

    The C-terminus is required for IGF-binding and growth inhibition.

  • Post-translational
    modifications

    O-glycosylated.

  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • Western blot - Recombinant human IGFBP2 protein (ab63223)
    Western blot - Recombinant human IGFBP2 protein (ab63223)

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