Recombinant Human ICA 512/PTPRN protein (ab42590)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Tags: GST tag N-Terminus
- Suitable for: Phosphatase Activity
-
Product name
Recombinant Human ICA 512/PTPRN protein -
Purity
> 95 % SDS-PAGE. -
Expression system
Escherichia coli -
Accession
-
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Predicted molecular weight
59 kDa including tags -
Amino acids
693 to 979 -
Tags
GST tag N-Terminus
-
Preparation and Storage
-
Alternative names
- CA 512
- FLJ16131
- IA 2
see all -
Function
Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2. -
Tissue specificity
Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary. -
Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
Contains 1 tyrosine-protein phosphatase domain. -
Post-translational
modificationsAppears to undergo multiple proteolytic cleavage at consecutive basic residues. -
Cellular localization
Membrane. Neuroendocrine secretory granules. - Information by UniProt
