Recombinant Human HGF protein (denatured) (ab181970)
Key features and details
- Expression system: Escherichia coli
- Purity: > 80% SDS-PAGE
- Suitable for: SDS-PAGE
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Product name
Recombinant Human HGF protein (denatured)
See all HGF proteins and peptides -
Purity
> 80 % SDS-PAGE. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MQRKRRNTIHEFKKSAKTTLIKIDPALKIK TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKK EFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH SYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCN GESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG QPRPWCYTLDPHTRWEYCAI KTCET -
Predicted molecular weight
30 kDa -
Amino acids
32 to 285 -
Additional sequence information
Mature sequence of Isoform 5 (NP_001010933).
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Description
Recombinant Human HGF protein
Preparation and Storage
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Alternative names
- DFNB39
- F TCF
- Fibroblast derived tumor cytotoxic factor
see all -
Function
Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. -
Involvement in disease
Deafness, autosomal recessive, 39 -
Sequence similarities
Belongs to the peptidase S1 family. Plasminogen subfamily.
Contains 4 kringle domains.
Contains 1 PAN domain.
Contains 1 peptidase S1 domain. - Information by UniProt