Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human HDGF protein (ab173057)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: HPLC, SDS-PAGE

Description

  • Product name

    Recombinant Human HDGF protein
    See all HDGF proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    The purity of ab173057 is greater than 95% ,as determined by SEC-HPLC and reducing SDS-PAGE. It is supplied as an 0.2 µM filtered solution.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    P51858

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFF GTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGY

    • Predicted molecular weight

      13 kDa including tags

    • Amino acids

      1 to 100

    • Tags

      His tag C-Terminus

    • Additional sequence information

      Sequence for the tag: LEHHHHHH

    • Specifications

    Our Abpromise guarantee covers the use of ab173057 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      HPLC

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.50
      Constituents: 0.24% Tris, 0.03% EDTA, 0.02% DTT

    General Info

    • Alternative names

      • FLJ96580
      • HDGF
      • HDGF_HUMAN
      • Hepatoma derived growth factor
      • Hepatoma-derived growth factor
      • High mobility group protein 1 like 2
      • High mobility group protein 1-like 2
      • HMG-1L2
      • HMG1L2
      see all

    • Function

      Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.

    • Tissue specificity

      Ubiquitous.

    • Sequence similarities

      Belongs to the HDGF family.
      Contains 1 PWWP domain.

    • Domain

      The PWWP domain harbors the heparin-binding sites and is responsible for DNA-binding, while the C-terminal region is essentially unstructured.

    • Post-translational
      modifications

      Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.

    • Cellular localization

      Cytoplasm. Nucleus.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab173057? Please let us know so that we can cite the reference in this datasheet.

ab173057 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.50
    Constituents: 0.24% Tris, 0.03% EDTA, 0.02% DTT

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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