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Signal Transduction Growth Factors/Hormones TGF

Recombinant Human GDF7 protein (ab115505)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 98% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, Functional Studies

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Description

  • Product name

    Recombinant Human GDF7 protein
  • Biological activity

    Determined by its ability to inhibit induced alkaline phosphatase production by ATDC5 chondrogenic cells.
  • Purity

    > 98 % SDS-PAGE.
    ab115505 is greater than 98% by SDS-PAGE gel and HPLC analyses.
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    Q75RY1
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      TALAGTRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFKELGWDDWIIAPL DYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLS PISILYIDAANNVVYKQYEDMVVEACGCR
    • Predicted molecular weight

      28 kDa
    • Amino acids

      322 to 450
  • Specifications

    Our Abpromise guarantee covers the use of ab115505 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      Functional Studies

    • Form

      Lyophilized
    • Additional notes

      Determined by its ability to inhibit induced alkaline phosphatase production by ATDC5 chondrogenic cells.
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    • Reconstitution
      Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.

    General Info

    • Alternative names

      • bmp12
      • bone morphogenetic protein 12
      • GDF-7
      • Gdf7
      • GDF7_HUMAN
      • growth differentiation factor 7
      • Growth/differentiation factor 7
      see all
    • Function

      May play an active role in the motor area of the primate neocortex.
    • Sequence similarities

      Belongs to the TGF-beta family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession Q7Z4P5 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab115505? Please let us know so that we can cite the reference in this datasheet.

    ab115505 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • bmp12
    • bone morphogenetic protein 12
    • GDF-7

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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