Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human GDF15 protein (ab50077)

Key features and details

  • Expression system: CHO cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant human GDF15 protein
    See all GDF15 proteins and peptides

  • Biological activity

    Determined by its ability to inhibit alkaline phosphatase activity in differentiating MC3T3/E1 osetoblast cells. The expected ED50 for this effect is 75-200 ng/ml.

  • Purity

    > 95 % SDS-PAGE.
    ab50077 purity was determined also by HPLC

  • Endotoxin level

  • Expression system

    CHO cells

  • Accession

    Q99988

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      ARNGDHCPLGPGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPS QFRAANMHAQIKTSLHRLKPDTVPAPCCVPASYNPMVLIQKTDTGVSLQT YDDLLAKDCHCI

    • Amino acids

      197 to 308

    • Additional sequence information

      This product refers to the processed mature form of this protein from aa 195 to 308. Therefore it does not contain the signal peptide or propeptide.

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab50077 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        Reconstitute to 1mg/ml with distilled water.

      General Info

      • Alternative names

        • GDF 15
        • GDF-15
        • Gdf15
        • GDF15_HUMAN
        • Growth differentiation factor 15
        • Growth/differentiation factor 15
        • Macrophage inhibitory cytokine 1
        • MIC 1
        • Mic-1
        • MIC1
        • NAG 1
        • NAG-1
        • NAG1
        • NRG 1
        • NRG-1
        • NRG1
        • NSAID
        • NSAID (nonsteroidal anti inflammatory drug) activated protein 1
        • NSAID regulated protein 1
        • NSAID-activated gene 1 protein
        • NSAID-regulated gene 1 protein
        • PDF
        • PLAB
        • Placental bone morphogenetic protein
        • Placental bone morphogenic protein
        • Placental TGF beta
        • Placental TGF-beta
        • Prostate differentiation factor
        • PTGF beta
        • PTGFB
        see all

      • Tissue specificity

        Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.

      • Sequence similarities

        Belongs to the TGF-beta family.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab50077? Please let us know so that we can cite the reference in this datasheet.

    ab50077 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • GDF 15
      • GDF-15
      • Gdf15
      • GDF15_HUMAN
      • Growth differentiation factor 15
      • Growth/differentiation factor 15
      • Macrophage inhibitory cytokine 1
      • MIC 1
      • Mic-1
      • MIC1
      • NAG 1
      • NAG-1
      • NAG1
      • NRG 1
      • NRG-1
      • NRG1
      • NSAID
      • NSAID (nonsteroidal anti inflammatory drug) activated protein 1
      • NSAID regulated protein 1
      • NSAID-activated gene 1 protein
      • NSAID-regulated gene 1 protein
      • PDF
      • PLAB
      • Placental bone morphogenetic protein
      • Placental bone morphogenic protein
      • Placental TGF beta
      • Placental TGF-beta
      • Prostate differentiation factor
      • PTGF beta
      • PTGFB
      see all

    • Tissue specificity

      Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.

    • Sequence similarities

      Belongs to the TGF-beta family.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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