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Signal Transduction Growth Factors/Hormones TGF

Recombinant Human GDF11 protein (ab50159)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant Human GDF11 protein
    See all GDF11 proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    Greater than 98% by SDS-PAGE. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    O95390
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
    • Amino acids

      299 to 407
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab50159 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized
      • Additional notes

         This product was previously labelled as BMP11, BMP11 + GDF8 / Myostatin

         

      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

      • Reconstitution
        For lot specific reconstitution information please contact our Scientific Support Team.

      General Info

      • Alternative names

        • BMP 11
        • BMP-11
        • BMP11
        • Bone morphogenetic protein 11
        • GDF 11
        • GDF-11
        • Gdf11
        • GDF11_HUMAN
        • Growth differentiation factor 11
        • Growth/differentiation factor 11
        see all
      • Function

        Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
      • Sequence similarities

        Belongs to the TGF-beta family.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession O95390 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab50159? Please let us know so that we can cite the reference in this datasheet.

    ab50159 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • BMP 11
      • BMP-11
      • BMP11
      • Bone morphogenetic protein 11
      • GDF 11
      • GDF-11
      • Gdf11
      • GDF11_HUMAN
      • Growth differentiation factor 11
      • Growth/differentiation factor 11
      see all
    • Function

      Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
    • Sequence similarities

      Belongs to the TGF-beta family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession O95390 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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