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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Recombinant human FSTL1/FRP protein (Active) (ab245801)

Key features and details

  • Expression system: CHO cells
  • Purity: > 95% SDS-PAGE
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE, HPLC

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Description

  • Product name

    Recombinant human FSTL1/FRP protein (Active)
    See all FSTL1/FRP proteins and peptides
  • Biological activity

    Measured by its binding ability in a functional ELISA. When ab245801 is coated at 200 ng/well, the concentration of recombinant human BMP-4 that produces 50% of the optimal binding response is found to be approximately 250 ng/mL.

  • Purity

    > 95 % SDS-PAGE.
    > 95 % by HPLC.
  • Expression system

    CHO cells
  • Accession

    Q12841
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      EEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNG KTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDE LRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLK FVEQNETAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLK CLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDGK NQKGAQTQTEEEMTRYVQELQKHQETAEKTKRVSTKEI
    • Predicted molecular weight

      33 kDa
    • Amino acids

      21 to 308
    • Additional sequence information

      Full length mature chain without signal peptide.

Preparation and Storage

  • Alternative names

    • Anti FSTL1
    • FLJ50214
    • FLJ52277
    • Follistatin like 1
    • Follistatin related protein
    • Follistatin-like protein 1
    • Follistatin-related protein 1
    • FRP
    • FSL1
    • FSTL1
    • FSTL1 antibody
    • FSTL1_HUMAN
    • Micro RNA 198
    • MIR198
    • miRNA198 included
    • OCC 1
    • OCC1
    see all
  • Function

    May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin.
  • Tissue specificity

    Overexpressed in synovial tissues from rheumatoid arthritis.
  • Sequence similarities

    Contains 2 EF-hand domains.
    Contains 1 follistatin-like domain.
    Contains 1 Kazal-like domain.
    Contains 1 VWFC domain.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession Q12841 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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  • Recombinant Human FSTL1/FRP protein (ab191942)

    Applications: HPLC, SDS-PAGE

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