Recombinant Human Ficolin 2 protein (ab158426)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
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Product name
Recombinant Human Ficolin 2 protein -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Sequence
MELDRAVGVLGAATLLLSFLGMAWALQAADTCPEVKMVGLEGSDKLTILR GCPGLPGAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLT GPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVD GSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFED NYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDN DLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGYN YSYKVSEMKVRPA -
Amino acids
1 to 313 -
Tags
GST tag N-Terminus
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Preparation and Storage
-
Alternative names
- 37 kDa elastin-binding protein
- Collagen/fibrinogen domain containing protein 2
- Collagen/fibrinogen domain-containing protein 2
see all -
Function
May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. -
Tissue specificity
Expressed by the liver and secreted in plasma. -
Sequence similarities
Belongs to the ficolin lectin family.
Contains 1 collagen-like domain.
Contains 1 fibrinogen C-terminal domain. -
Domain
The fibrinogen-like domain (FBG) contains potential calcium-binding sites that may be involved in carbohydrate binding. -
Cellular localization
Secreted. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human Ficolin 2 protein (ab158426)ab158426 on a 12.5% SDS-PAGE stained with Coomassie Blue.