Recombinant Human EPCR/CD201 protein (Fc Chimera) (ab221306)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Suitable for: SDS-PAGE
Preparation and Storage
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Alternative names
- Activated protein C receptor
- APC receptor
- APCR
see all -
Function
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation. -
Tissue specificity
Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. -
Post-translational
modificationsN-glycosylated.
A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human EPCR/CD201 protein (Fc Chimera) (ab221306)
SDS-PAGE - Human EPCR/CD201 protein (Fc Chimera) (ab221306)
Lane 1: DTT-reduced.
Lane 2: Non-reduced.
Staining overnight with Coomassie Blue.
