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Signal Transduction Protein Phosphorylation Tyrosine Kinases Receptor Tyrosine Kinases

Recombinant human EGFR (mutated D770G + D770Y) protein (Active) (ab268480)

Recombinant human EGFR (mutated D770G + D770Y) protein (Active) (ab268480)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Baculovirus infected Sf9 cells
  • Purity: > 85% SDS-PAGE
  • Active: Yes
  • Tags: GST tag N-Terminus
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant human EGFR (mutated D770G + D770Y) protein (Active)
    See all EGFR proteins and peptides
  • Biological activity

    The specific activity of ab268480 was determined to be 52 nmol/min/mg in a kinase assay using Poly (Glu4, Tyr1) synthetic peptide substrate.

  • Purity

    > 85 % SDS-PAGE.

  • Expression system

    Baculovirus infected Sf9 cells
  • Accession

    P00533
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Molecular weight information

      SDS-PAGE molecular weight: ~89-100kDa
    • Amino acids

      668 to 1210
    • Modifications

      mutated D770G + D770Y
    • Tags

      GST tag N-Terminus
    • Additional sequence information

      NM_005228. Cytoplasmic domain. Mutation: D770GY

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.50
    Constituents: 0.79% Tris HCl, 0.87% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.004% DTT, 0.002% PMSF, 25% Glycerol (glycerin, glycerine)

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

Images

  • Functional Studies - Recombinant human EGFR (mutated D770G + D770Y) protein (Active) (ab268480)
    Functional Studies - Recombinant human EGFR (mutated D770G + D770Y) protein (Active) (ab268480)

    The specific activity of ab268480 was determined to be 52 nmol/min/mg in a kinase assay using Poly (Glu4, Tyr1) synthetic peptide substrate.

  • SDS-PAGE - Recombinant human EGFR (mutated D770G + D770Y) protein (Active) (ab268480)
    SDS-PAGE - Recombinant human EGFR (mutated D770G + D770Y) protein (Active) (ab268480)

    SDS-PAGE analysis of ab268480.

    MW ~89-100 kDa.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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