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Signal Transduction Growth Factors/Hormones Hormones

Recombinant Human ECE1 protein (His tag) (ab276334)

Recombinant Human ECE1 protein (His tag) (ab276334)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag N-Terminus
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human ECE1 protein (His tag)
    See all ECE1 proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    P42892
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      QYQTRSPSVC LSEACVSVTS SILSSMDPTV DPCHDFFSYA CGGWIKANPV PDGHSRWGTF SNLWEHNQAI IKHLLENSTA SVSEAERKAQ VYYRACMNET RIEELRAKPL MELIERLGGW NITGPWAKDN FQDTLQVVTA HYRTSPFFSV YVSADSKNSN SNVIQVDQSG LGLPSRDYYL NKTENEKVLT GYLNYMVQLG KLLGGGDEEA IRPQMQQILD FETALANITI PQEKRRDEEL IYHKVTAAEL QTLAPAINWL PFLNTIFYPV EINESEPIVV YDKEYLEQIS TLINTTDRCL LNNYMIWNLV RKTSSFLDQR FQDADEKFME VMYGTKKTCL PRWKFCVSDT ENNLGFALGP MFVKATFAED SKSIATEIIL EIKKAFEESL STLKWMDEET RKSAKEKADA IYNMIGYPNF IMDPKELDKV FNDYTAVPDL YFENAMRFFN FSWRVTADQL RKAPNRDQWS MTPPMVNAYY SPTKNEIVFP AGILQAPFYT RSSPKALNFG GIGVVVGHEL THAFDDQGRE YDKDGNLRPW WKNSSVEAFK RQTECMVEQY SNYSVNGEPV NGRHTLGENI ADNGGLKAAY RAYQNWVKKN GAEHSLPTLG LTNNQLFFLG FAQVWCSVRT PESSHEGLIT DPHSPSRFRV IGSLSNSKEF SEHFRCPPGS PMNPPHKCEV W
    • Predicted molecular weight

      80 kDa including tags
    • Molecular weight information

      The recombinant human ECE1 comprises 698 amino acids and has a predicted molecular mass of 80 kDa. As a result of glycosylation, rh ECE1 migrates as an approximately 125 kDa band in SDS-PAGE under reducing conditions.
    • Amino acids

      90 to 770
    • Tags

      His tag N-Terminus
    • Additional sequence information

      Predicted N-terminus: His.
  • Specifications

    Our Abpromise guarantee covers the use of ab276334 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • ECE
      • ECE 1
      • ECE-1
      • ECE1
      • ECE1_HUMAN
      • Endothelin converting enzyme 1
      • Endothelin-converting enzyme 1
      see all
    • Relevance

      Function: Converts big endothelin-1 to endothelin-1. Tissue specificity: All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A and C in liver, testis and small intestine; isoform B, C and D in endothelial cells and umbilical vein smooth muscle cells; isoforms C and D in saphenous vein cells, and isoform C in kidney. Disease: Hirschsprung disease cardiac defects and autonomic dysfunction Similarity: Belongs to the peptidase M13 family.
    • Cellular localization

      Cell Membrane. Single pass type II membrane protein.

Images

  • SDS-PAGE - Recombinant Human ECE1 protein (ab276334)
    SDS-PAGE - Recombinant Human ECE1 protein (ab276334)
    SDS-PAGE analysis of ab276334

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab276334? Please let us know so that we can cite the reference in this datasheet.

    ab276334 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • ECE
    • ECE 1
    • ECE-1

    Images

    • SDS-PAGE - Recombinant Human ECE1 protein (ab276334)
      SDS-PAGE - Recombinant Human ECE1 protein (ab276334)
      SDS-PAGE analysis of ab276334

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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