Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human CXCL16 protein (ab50175)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: SDS-PAGE, Functional Studies

Description

  • Product name

    Recombinant human CXCL16 protein
    See all CXCL16 proteins and peptides

  • Biological activity

    Biological Activity : Determined by it's ability to chemoattract activated lymphocytes using a concentration of 1.0-100.0 ng/ml.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      NEGSVTGSCY CGKRISSDSP PSVQFMNRLR KHLRAYHRCL YYTRFQLLSW SVCGGNKDPW VQELMSCLDL KECGHAYSGI VAHQKHLLP

    • Amino acids

      49 to 137

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab50175 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        Functional Studies

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        Reconstitute to 1mg/ml in sterile water.

      General Info

      • Alternative names

        • C-X-C motif chemokine 16
        • Chemokine (C X C motif) ligand 16
        • Chemokine, CXC motif, ligand 16
        • CXC chemokine ligand 16
        • Cxcl16
        • CXCLG16
        • CXL16_HUMAN
        • Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
        • SCYB16
        • Small inducible cytokine B16 precursor
        • Small-inducible cytokine B16
        • SR-PSOX
        • SRPSOX
        • Transmembrane chemokine CXCL16
        • UNQ2759/PRO6714
        see all

      • Function

        Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.

      • Tissue specificity

        Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.

      • Sequence similarities

        Belongs to the intercrine alpha (chemokine CxC) family.

      • Post-translational
        modifications

        Glycosylated.

      • Cellular localization

        Cell membrane. Secreted. Also exists as a soluble form.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab50175? Please let us know so that we can cite the reference in this datasheet.

    ab50175 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • C-X-C motif chemokine 16
      • Chemokine (C X C motif) ligand 16
      • Chemokine, CXC motif, ligand 16
      • CXC chemokine ligand 16
      • Cxcl16
      • CXCLG16
      • CXL16_HUMAN
      • Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
      • SCYB16
      • Small inducible cytokine B16 precursor
      • Small-inducible cytokine B16
      • SR-PSOX
      • SRPSOX
      • Transmembrane chemokine CXCL16
      • UNQ2759/PRO6714
      see all

    • Function

      Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.

    • Tissue specificity

      Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.

    • Sequence similarities

      Belongs to the intercrine alpha (chemokine CxC) family.

    • Post-translational
      modifications

      Glycosylated.

    • Cellular localization

      Cell membrane. Secreted. Also exists as a soluble form.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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